Advancexo
4 min readJan 20, 2023

Exosome skin care — what is it and how does it work?

Exosomes for Skin Care

Exosome skin care is receiving attention as an excellent method of skin regeneration. Exosome skin care attempts to do just that as more and more therapies emerge that concentrate on thoroughly repairing the skin to reverse the effects of ageing. Exosome, a component of exosome skin care, targets this damage. But how does this treatment function?

What are Exosomes?

Exosomes are nanoparticles secreted by almost all cells within the body, and skin cells produce a unique type of exosome. The lipids, proteins, amino acids, peptides, growth factors, and the genetic material they contain are diverse. They operate by exchanging information and signals between cells. You might see them as messengers who convey signals to sick cells to encourage their regeneration. Exosomes, therefore, activate the body’s inherent ability to heal.

Exosomes are isolated from human stem cells and frozen to preserve them for use in in-office skin-care procedures. Exosomes lack a nucleus in contrast to actual stem cells. She continues that because they are only mRNA, there is no risk of an adverse graft-versus-host reaction.

Exosomes as natural ingredients for skin care entails the use of topical exosomes in what appears and feels like a skin stem cell serum or gel. Exosomes, which can only be used in conjunction with in-office treatments, are like the icing on the cake.

How does it Benefit the Skin?

According to dermatologists, as we age, the skin cells begin to atrophy and our bodies create fewer exosomes, which is comparable to how we experience a decline in collagen formation. This causes drooping, wrinkles, and fine lines. Exosomes enable older exosomes and fresh exosomes to reawaken dormant skin cells and resume their reparative, strengthening, and regenerating functions. It speeds up wound healing, boosts the creation of collagen and elastin, and reduces the development of pigment.

Exosomes have even been revealed in a recent study to contain anti-inflammatory capabilities that can help reduce the signs and symptoms of inflammatory skin disorders including psoriasis and atopic dermatitis (also known as eczema).

The Function of Exosomes

The proteins and nucleic acids are contained in an intraluminal gap inside the exosome sphere, which keeps them from deteriorating. Exosomes communicate with recipient cells through ligands and surface receptor molecules. Exosomes are internalised by endocytosis when they are bound by surface receptors. RNA and protein transferring across cells is made possible by this!

Exosomes affect other cells by:

  • Immune system performance
  • wound recovery
  • metabolic engineering

Exosomes in Cosmetics

Exosomes differ significantly in their origin, isolation techniques, size, and composition. It is crucial to realize that different exosomes have different functions. Here is when the flaw in cosmeceutical promises starts to show itself. A product has not necessarily been demonstrated to work just because exosomes are present in it. Before you become enthusiastic about one of these exosome-containing skin care products, make sure you are aware of the exosomes’ origin and the supporting scientific evidence.

Recent studies on Exosomes

  • Topical application of exosomes following micro needling

Exosomes made from mesenchymal stem cells were applied to microneedle skin and improved the look of the skin. Microneedling injury generates an inflammatory trigger that prompts the exosomes to produce regenerative signals in response. This study unequivocally demonstrated that skin renewal occurs after micro needling when the proper kind of exosomes are applied.

  • Applying twice daily topical platelet-derived exosomes to mature skin

56 volunteers at the Mayo Clinic received twice daily applications of topical platelet-derived exosomes on aged skin for a period of six weeks. Decreased redness and improved wrinkles indicate a statistically significant improvement in skin health. It received good reviews and was safe. It is undeniable that the results are influenced by the exosomes’ origin, quality, and quantity. Because of this, we must urge that manufacturers of skin care products divulge information on the kinds of exosomes they use in their anti-aging products.

The Upshot

For regenerative health of the face and hair growth, Exosomes skin care products are the hot topic, the most innovative treatment now accessible. It’s not surprising that this incredible product has gained a lot of attention in the community because it delivers results that measure up to the buzz and requires no surgery. Extracellular vesicles, also known as pure exosomes, are able to target areas of inflammation and injury to encourage cellular regeneration, stimulate collagen formation, and drastically improve skin quality and complexion when used in conjunction with various other skin treatments.

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Advancexo
Advancexo

Written by Advancexo

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